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KMID : 0903519840270020095
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Journal of the Korean Society of Agricultural Chemistry and Biotechnology
1984 Volume.27 No. 2 p.95 ~ p.99
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Synthesis and Antifungal Activity of 3 - Oxo - 1,2 - benzisothiazole - 1,1 - dioxide Derivatives
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Kim In-Kyu
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Abstract
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Some derivatives of 3-oxo-1,2-benzisothiazole-1,1-dioxide were synthesized, and their antifungal activities against Pyricularia oryzae was determined by the agar medium dilution method.
I_(50) values of the candidate derivatives were shown to be as follows; 3-chloro(37.8ppm), 2-chloro(318.7ppm), MCS(20.1ppm), 2-allyl(946.2ppm), 3-(p-nitrophenyloxy) (35.4ppm), 3-(o-nitrophenyloxy) (11.8ppm), 3-(p-aminophenyloxy) (1643.2ppm), 2-chloromethyl(192.7ppm) and 2-hydroxymethyl derivative(248.4ppm).
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